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June 13, 1925


JAMA. 1925;84(24):1818-1819. doi:10.1001/jama.1925.02660500026014

The frequency of gonococcus infections of the seminal duct has long dominated our conception of epididymitis and vesiculitis, which are commonly assumed to arise by invasion from the urethra only, and to interest merely urologists. That these organs are infected by parasites floating in the blood also has in recent years attained an importance demanding recognition by clinicians in general.

Three items in the physiology of the seminal ducts are recalled: 1. The epididymis, which is by derivation the kidney of the cold-blooded animals (Fig. 1), may, like its successor the mammalian kidney, excrete the virus of the blood infections; epididymitis is a known feature of tuberculosis, syphilis, typhoid fever, malaria and influenza; and in the inflamed epididymis have been identified all the pathogenic organisms known to be excreted by the kidney.

2. The contents of the epididymis, abnormal as well as normal, pass through the vas deferens and accumulate

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