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Article
June 27, 1925

THE FUNGICIDAL ACTIVITY OF CERTAIN VOLATILE OILS AND STEAROPTENS: THEIR COMPARATIVE TOXICITY ON A PATHOGENIC YEASTLIKE ORGANISM: REPORT OF CLINICAL UTILIZATION IN RELATED INFECTIONS

Author Affiliations

PORTLAND, ORE.
From the Department of Pharmacology, University of Oregon Medical School.

JAMA. 1925;84(26):1985-1986. doi:10.1001/jama.1925.02660520013005
Abstract

The fruit packing plants of the Pacific Northwest have been troubled for several years with a dermatosis developing among employees engaged in preparing the fruit for canning. The lesion has been referred to by those affected as a "fruit poisoning." It has been treated without much success by a great variety of means, chiefly by the antiseptics commonly utilized in treating bacterial infections.

A person with an interdigital lesion that originated while employed in one of the fruit packing plants came to our attention a few months ago. The infection referred to had persisted for several months in spite of the use of various prescribed standard antiseptics. Scrapings from the lesion revealed budding spore forms with mycelium attached, which we believed to be responsible for the inflammatory reaction. A 10 per cent. alcoholic solution of the oil of cinnamon was painted over the inflamed area. Rapid improvement in the appearance

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