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August 8, 1925

A CASE OF "HEMORRHAGIC ENCEPHALITIS" TREATED WITH SODIUM THIOSULPHATE

Author Affiliations

Richmond, Va. Instructor in Medicine, Medical College of Virginia
From the Department of Internal Medicine, Medical College of Virginia, Hospital Division.

JAMA. 1925;85(6):436-437. doi:10.1001/jama.1925.26710060002012b
Abstract

McBride1 recently reported a case of hemorrhagic encephalitis treated with sodium thiosulphate. In this report the author states that "nowhere has been noted the use of sodium thiosulphate in the condition spoken of as "hemorrhagic encephalitis." Another case of the same condition treated with sodium thiosulphate, with unfortunately not the result that was noted in McBride's case, is here reported. In this case, as in McBride's, the "encephalitis" followed sulpharsphenamin injection.

REPORT OF CASE  J. A., a white man, aged 33, was brought, March 17, 1925, to the hospital division in a semiconscious state. The history was obtained from the patient's private physician, who stated that he had treated the patient prophylactically for syphilis. The physician stated that he had treated the patient's wife for syphilis prior to her marriage, that she had had a miscarriage four months before her marriage, and that her blood Wassermann reaction was strongly

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