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December 1, 1923


Author Affiliations

From the Hull Laboratory of Physiology, University of Chicago, and the Presbyterian Hospital.

JAMA. 1923;81(22):1851-1857. doi:10.1001/jama.1923.02650220021006

Several months ago, a preliminary report was published on the use of ethylene gas as an anesthetic in a series of 106 operative cases.1 A previous report presented a rather detailed study of the physiologic action of the gas on the usual laboratory animals, including a number of normal men.2 Since that time the number of operations performed at the Presbyterian Hospital, Chicago, has risen to some 800. In the preliminary communication on the clinical phases of the work, certain important facts received no mention at all, and others were ascertained only as the work progressed. Our attention was furthermore called3 to some earlier literature on ethylene which we had overlooked in spite of what we considered a thorough search.4 These reasons have prompted us to issue this report.

LITERATURE  Before presenting the reader with a brief chronological report on the real and alleged studies on