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December 15, 1923


JAMA. 1923;81(24):2030-2031. doi:10.1001/jama.1923.02650240034011

In 1918 we 1 described a family that presented what appeared to be a new form of hereditary hemorrhagic disease distinct from the two already established forms of bleeding tendency, hemophilia and multiple telangiectases. In this family, seven persons presented almost identical histories of repeated profuse hemoptyses beginning about puberty or in early adult life and occurring at intervals throughout life.

We have now kept three bleeders in this family under observation for an additional five years since our first report, (through the courtesy of Dr. S. S. Lubin, their family physician). This makes a total of seven years during which the clinical picture of the condition has been observed and has not changed. We think that this long period of observation is sufficient to exclude tuberculosis.

The first member of the family to be seen by us was admitted to the Mount Sinai hospital in 1916, while suffering from