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September 19, 1925


JAMA. 1925;85(12):903-904. doi:10.1001/jama.1925.02670120041016

One reason why experimentation on animals has yielded so much information of value in relation to the physiology and pathology of man lies in the possibilities it affords for direct observation of functions that cannot readily be studied in the same way during life in the human organism. In the case of sensations, however, the situation is not so simple. The interpretation of sensations, so far as they may arise in animals, offers many difficulties. Frequently the existence of certain sensory states can only be postulated because of some associated phenomena. Nausea is a sensation; consequently, as a recent writer1 has pointed out, its presence must be identified with some objective or motor manifestation before it can be studied effectively by animal experimentation.

For this reason the mechanism responsible for the genesis of nausea has not yet been clearly expounded. Keeton1 of Chicago has recently recorded the sensations