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September 26, 1925


Author Affiliations

From the service of Dr. Williams at the New York Skin and Cancer Hospital.

JAMA. 1925;85(13):955-958. doi:10.1001/jama.1925.02670130017005

Every dermatologist has observed the peculiar mottling of the skin that sometimes occurs when the body is exposed to the cold. It is so common an occurrence that no attention is paid to it, beyond noting that it is not an early macular syphilid. And yet the phenomenon is not universal—many patients show no such mottling. What is the cause of the difference? It is a question that has not yet been answered, principally because the condition is so transitory and unimportant that very few have given any study to it. The words cutis marmorata and livedo, which have been applied to this condition, are not to be found in the indexes of most of our dermatologies. Mild as it is, this rash is only the first member of a long series, gradually increasing in extent and in severity, constituting, in the more severe cases, a permanent disfigurement. There is

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