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December 29, 1923


Author Affiliations

Attending Physician, Cook County Hospital, Children's Department; Instructor of Pediatrics, Rush Medical College CHICAGO

JAMA. 1923;81(26):2181-2182. doi:10.1001/jama.1923.02650260023007

The occurrence of mongolism in twins seems worthy of report not only because of its great rarity but because of its possible bearing on the question of whether an endogenic or exogenic factor is involved in the etiology of this anomaly.

REPORT OF CASE  The parents of the twins affected with mongolian idiocy were healthy, very intelligent and without any inherited taint. Neither of them was syphilitic or alcoholic. The mother at the time of conception was 20 years of age, and the father, 30½. The pregnancy was without any disturbance. The twins were the first born of the family; the three other children, aged 7, 4¾, and 1½ years were perfectly healthy and intelligent.The twins were born, March 21, 1915, at the end of the eighth month of gestation; the first infant, weighing 5 pounds, 12 ounces (2.6 kg.), was delivered by forceps; the second infant, weighing 5