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October 10, 1925


JAMA. 1925;85(15):1140. doi:10.1001/jama.1925.02670150038015

It has become well established in recent years that certain disorders of the eye may be closely associated with malnutrition. The possibility of such an interrelationship was long suspected, but it remained for the more modern methods of investigation in the field of nutrition to replace conjecture by scientific demonstrations. An illuminating illustration is furnished by the experimental production of xerosis conjunctivae, or xerophthalmia, under conditions of diet in which there is a deficiency of vitamin A. The eye symptoms thereby observed in animals are identical in various respects with those noted in man; and they are relieved or averted, as the case may be, by similar therapeutic measures that depend on supplying the missing food factor.

There is another ocular disorder, night blindness, that has been ascribed to faulty diet among other explanations of its etiology. We are not referring here to congenital night blindness, or to the night