This is a study of pupillary inequality in connection with pulmonary tuberculosis. The author takes up the anatomy and physiology of the iris and then offers his experimental study, based on seventy cases. He points out the difficulty which others have experienced in their endeavor to determine the inequality of one or the other pupil. After showing the various methods of such determination, he has decided that mydriasis is of the most use. It was found that among sixty-one cases of unilateral pulmonary tuberculosis, there were forty-two which presented equal pupils, while nineteen showed inequalities (anisocoria). Among bilateral cases, inequality of the pupils was found only five times. After some further discussion, the author concludes that there is no hard and fast connection between a pupillary inequality and pulmonary tuberculosis, whether on one or on both sides. In almost the closing paragraph the statement is made that "it is syphilis