The successful use of foreign protein injections for ocular disease dates from 1915, when it occurred to Schmidt1 of Prague to use cow's milk for these injections. He chose milk because it was easy to procure and because the chemical composition of this animal secretion is a constant, whereas the composition of artificial preparations of proteins and their derivatives is subject to considerable variation. Since Schmidt's first report on the use of milk injections in ocular, as well as in general, disease, milk has been used in many thousands of cases by ophthalmologists, often with striking benefit. The literature is full of reports of good clinical results, and from personal experience we can heartily endorse the use of milk in certain kinds of ocular disease. There is no doubt of its efficacy in iritis, iridocyclitis and gonorrheal conjunctivitis, and as a prophylactic in infections of the eyeball following perforating
BARKAN O, NELSON RF. THE ACTIVE AGENT IN MILK INJECTIONS. JAMA. 1924;82(3):190–193. doi:10.1001/jama.1924.02650290020004
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