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January 26, 1924


JAMA. 1924;82(4):303. doi:10.1001/jama.1924.26520300002014b

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Mrs. M. N., aged 48, complained for one year of attacks of pain in the upper right abdomen. The pain was very severe, of a colicky nature, and extended across the upper abdomen and to the back. It usually came on during the night and bore no relation to eating or posture. She felt distended after eating, and usually brought up considerable gas. She had always been constipated, but more so for the past six months, and suffered frequently with indigestion and "bilious spells." Following one severe attack of pain three months before I saw her, she stated that the stools were very light, but jaundice was not perceptible. The physical examination was negative, except for marked tenderness over the gallbladder.

June 23, 1923, the gallbladder was drained according to the Meltzer-Lyons method. Within ten minutes after the injection of the magnesium sulphate, bile began to flow, and 6 ounces

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