The study of the thymic shadow shown on the roentgenogram was undertaken in the Newly Born Service of Touro Infirmary about three years ago with the idea of arriving at some definite conclusions as to the size, shape and position of the thymus. Examinations were made, beginning during the first twenty-four hours of birth, up to the present time, and an endeavor was made to show what type was causing the peculiar syndrome that we see in children.
The first authentic description of this clinical picture was in Rokitansky's textbook, which appeared in 1861. He described a general hyperplasia of all the lymphatic structure, with an especial reference to the increase in the size of the thymus. Arnold Platauf, in an article published in 1889, still adhered to Rokitansky's theory of a specific constitutional anomaly. Sheila, in 1876, showed that the specific thymic extract, when injected, produced a long train
DE BUYS LR, SAMUEL EC, BOWIE ER. THYMUS AND THE TREATMENT OF ITS HYPERFUNCTION: CLINICAL AND ROENTGENOLOGIC CONSIDERATIONS. JAMA. 1925;85(20):1551–1553. doi:10.1001/jama.1925.02670200029007
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