[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 35.173.48.53. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
November 14, 1925

CONVALESCENT SERUM IN PREPARALYTIC CASES OF POLIOMYELITIS: RESULTS OF INTRAMUSCULAR ADMINISTRATION

Author Affiliations

SAN FRANCISCO
From the Department of Pediatrics, University of California Medical School, and the Children's Hospital, San Francisco.

JAMA. 1925;85(20):1555-1558. doi:10.1001/jama.1925.02670200033009

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

The brilliant observations of Levaditi and Landsteiner, Römer and Joseph, Flexner and Lewis, and Anderson and Frost that immunity or neutralizing substances to the poliomyelitis virus are present in the blood serum of recovered monkeys and human beings were followed fairly promptly by the reports of Netter and his associates in France and later by Amos and his co-workers in this country on the use of convalescent serum in the treatment of the disease. The French investigators used the subdural method of injection and believed that they had unquestionably proved the procedure to be of value. They stressed the time element particularly and urged that the injections be given in the earliest stages of the disease. The American observers employed the intraspinal and intravenous routes either directly into the blood vessels or indirectly by way of the subcutaneous tissues, and their results certainly justified their conclusions, that the earlier in

First Page Preview View Large
First page PDF preview
First page PDF preview
×