Any test that offers even only presumptive evidence of the presence or absence of pregnancy, from conception to the third month, must obviously be of great value. Attempts to provide such tests are reflected in the complement deviation test, Abderhalden's dialysis test, interdermal reactions and the like. More recently the phenomena of renal glycosuria, epinephrin glycosuria and phlorizin glycosuria have come under investigation. In the last two years the literature 1 on this subject has been growing rapidly, chiefly in the German journals.
Our experience with some of these tests warrants the following conclusions:
Renal glycosuria, after 100 gm. of glucose, in pregnancy during the first three months, is a diagnostic sign of great value and a high degree of accuracy.
Phlorizin glycosuria is of little value, is at times misleading, and should be abandoned as a practical measure.
In March, 1921, we encountered, in a multipara, pregnant eight months,
MILNOR GC, FENNEL EA. THE DIAGNOSIS OF PREGNANCY. JAMA. 1924;82(7):538–540. doi:10.1001/jama.1924.02650330030010
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