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November 21, 1925


JAMA. 1925;85(21):1652. doi:10.1001/jama.1925.02670210054021

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The Viruses of Vaccinia and Variola  Dr. Mervyn Gordon, F.R.S., has reported to the Medical Research Council researches which he has made on the viruses of vaccinia and variola and which seem to constitute an important advance and throw light on the disputed question whether the mild form of smallpox that has recently prevailed in this country and has been termed alastrim is a separate disease or not. Dr. Gordon employed the skin of the rabbit as a reagent for detecting the presence of vaccinia virus and made his tests quantitative by diluting his material to a known degree. Specific antibodies appeared in the blood of the rabbit after inoculation with vaccinia, and the serum was found protective to other rabbits against the disease. The virus of vaccinia was affected by gravity, for it could be spun down to the bottom of a tube by centrifugalization. A suspension of vaccinia

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