Classifications of nephritis, whether suggested by clinicians or by pathologists, usually are very complex. It has seemed to me that these classifications, by reason of their complexity, are of less service in the clinic, because it is so difficult to fit the patients into them, and because so often there is a failure of agreement between the predicted and the actual anatomic changes in the kidney.
My own experience has been that, even with the application of both the old and the new methods available for diagnosis, it is not possible to diagnose accurately, during life, the anatomic changes that will be found in the kidneys after death. This is not to say that, from certain groupings of symptoms and clinical findings, one may never prophesy correctly what the pathologist will find at necropsy; but the errors are sufficiently frequent to justify much skepticism of one's ability to correlate clinical
CHRISTIAN HA. CLASSIFICATION OF CHRONIC NEPHRITIS. JAMA. 1925;85(22):1701–1702. doi:10.1001/jama.1925.02670220019006
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