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November 28, 1925


JAMA. 1925;85(22):1743-1745. doi:10.1001/jama.1925.02670220061028

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Quinin Prophylaxis in Malaria  In the crusade against malaria through prophylaxis by quinin the findings seem contradictory. In malarial regions therapeutic doses of quinin are necessary to adequate prophylaxis. Dr. Nicolai recently published his results in a group of laborers in the Dutch East Indies to whom he applied the Ziemann treatment. This is based on the belief that injection of 1 gm. of quinin maintains resistance for four days, since quinin may be recovered from the urine for three successive days. Nicolai, however, noted absence of quinin after thirty-eight hours in 20 per cent, of the cases and after forty-eight hours in the majority of the cases. He could not see that either the number of new cases or the relapses was notably decreased.

The Antimalaria Crusade  The official antimalaria crusade has been replaced by an antimalaria organization that appeals chiefly to the people. The only official body in

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