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December 19, 1925


JAMA. 1925;85(25):1985-1986. doi:10.1001/jama.1925.02670250059027

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To the Editor:  —In a communication in The Journal, September 26 (page 995), Dr. George Draper makes certain points with which I must disagree. With one, however, the necessity for a preparalytic diagnosis to secure the best results in any form of serum treatment, all clinicians will heartily concur.Dr. Draper favors the use of serum from patients recovered from acute poliomyelitis and cites a specific case in which, by the administration of such serum, a baby with infantile paralysis recovered without the onset of paralysis. He acknowledges that previous reports of the use of serum from recovered patients with poliomyelitis have not been encouraging, but attributes this to the giving of insufficient serum.The proper dose, according to Dr. Draper, should be 15 c.c. intraspinally, with from 150 to 200 c.c. of serum intravenously, requiring about 500 c.c. of blood. He thinks that the blood might either be secured

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