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December 26, 1925


JAMA. 1925;85(26):2045-2046. doi:10.1001/jama.1925.02670260043022

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Cerebrospinal Meningitis  From his experience in the army of occupation, Dr. Muschang points out some facts concerning symptomatology of cerebrospinal meningitis. In addition to the outstanding symptoms, there are irregularity of the pulse, herpes labialis and petechial purpuric eruptions. In infants, abnormal tension of the fontanels is of high diagnostic value. Ocular signs, rapid coagulation of the cerebrospinal fluid and xanthochromia are of great importance. From the therapeutic standpoint, he recommends: (1) injection of serum into the vertebral canal; (2) prompt action; (3) large doses: withdrawal of 50 c.c. of cerebrospinal fluid, injection of 40 c.c. of serum, this dose to be repeated systematically for four days and combined with 40 c.c. of serum intramuscularly, and (4) specificity in the serotherapy: polyvalent serum, and, as soon as the laboratory has identified the causative meningococcus, injection of anti-A, anti-B or anti-C serum.

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