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December 26, 1925


JAMA. 1925;85(26):2049. doi:10.1001/jama.1925.02670260047028

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To the Editor:  —In the Rio de Janeiro letter (The Journal, November 28) appears the abstract of a report by Dr. Moreira de Fonseca, dealing with a matter entitled symmetrical cyanoderma.The description of the eruption is meager, but, judging from the brief account, the lesions and their mode of involution are very strongly suggestive of an eruption due to either phenolphthalein or antipyrin, administered by mouth.It would be unwise to burden our overcrowded dermatologic nomenclature with the term "symmetrical cyanoderma," for it might be readily confused with such diseases as erythromelalgia, Raynaud's disease, pernio and erythredema.

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