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Article
January 2, 1926

PITUITARY DISEASE IN A BOY, AGED FOUR

JAMA. 1926;86(1):31-32. doi:10.1001/jama.1926.26720270001008

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Abstract

R. B. was admitted to the surgical ward after an automobile accident, suffering from minor abrasions of the face, and a slight scalp laceration. He appeared to be about 10 years of age; he was well developed, but had an unusually well developed penis, like that of an adult, and an abundance of pubic hair. On the arrival of his father, it was ascertained that the boy was 4 years of age.

He was born, April 15, 1921, of normal delivery, at home, and weighed 9½ pounds (4.3 kg.). At the age of 1 month, the mother noticed that the bowels were habitually constipated. She then gave him daily cathartics. He was breast fed until 4 months old. After that he was given 4 ounces (120 c.c.) of whole milk every three or four hours. At the age of 14 months he had an attack of convulsions, followed by two

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