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March 22, 1924


Author Affiliations

From the Section on Orthopedic Surgery, Mayo Clinic.

JAMA. 1924;82(12):945-949. doi:10.1001/jama.1924.02650380013004

Localized proliferative chronic nonsuppurative sclerosing osteitis is revealed in the roentgenogram by a spindle-shaped thickening of the bone. The medullary cavity is reduced in size, and the bone is increased in density. The pain is a deep aching, usually worse at night and on exertion. The lower extremity is more often involved; there is local swelling, local heat, and often tenderness on deep pressure. The condition is sufficiently rare to confuse even surgeons of wide experience.

The literature on the subject is not abundant. Gosselin,1 in 1868, gave a good description of the condition. Cheyne,2 in 1890, described a case of osteitis in the radius in which, at operation, a sequestrum was removed without a trace of pus being encountered. Kluppel,1 in 1879, recorded the condition in the femur of a boy, aged 12 years. Garré's 3 classical description appeared in 1893, after which the condition was