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Article
March 22, 1924

NEPHRITIS IN EPIDEMIC ENCEPHALITIS: CLINICAL AND PATHOLOGIC REPORT, ILLUSTRATING THE DIFFICULTY IN DIAGNOSIS FROM MYOCLONIC UREMIA

Author Affiliations

PHILADELPHIA
From the clinical and pathologic records of the Philadelphia General Hospital.

JAMA. 1924;82(12):957-960. doi:10.1001/jama.1924.02650380025009
Abstract

The occurrence of nephritis not infrequently complicating acute cases of epidemic encephalitis in the Philadelphia General Hospital, and one case of nephritis which seemed to be a sequel of the disease, has prompted this report.

In a review of the voluminous literature of epidemic encephalitis, one is struck by the few instances in which detailed pathologic studies of the general viscera have been reported. It would seem that the only focus of pathologic study has been on the central nervous system. This tract, of course, should receive the more careful study, but it is hoped that this report may stimulate further investigation of pathologic changes in the viscera, in order to determine the extraneurologic complications of the disease. In the pathologic reports of organs they are, as a rule, given in a few words. A few observers have noted petechial hemorrhages of serous surfaces, resembling those seen in septicemia. The

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