Whooping cough still remains a source of a far from negligible mortality and of a great morbidity in childhood. A disease that causes 10,000 deaths in one year in the United States is certainly a serious menace. Yet this does not take into consideration the mortality indirectly attributable to it from predisposition to other infections, notably tuberculosis, nor does it take into account the morbidity resulting from it due to the persistent alterations induced so often in the bronchopulmonary tract; nor, indeed, can any calculation be made that would adequately express the detrimental effect on the nutritional status of the patient, a condition that probably persists often for a prolonged period of time.
In the study of pertussis there has not, it appears, been as much attention given to the chemical analysis of the composition of the blood as it would seem is merited by the importance of this aspect
REGAN JC, TOLSTOOUHOV AV. CHARACTERISTIC CHANGES IN BLOOD CHEMISTRY IN WHOOPING COUGH. JAMA. 1926;86(3):181–182. doi:10.1001/jama.1926.02670290021007
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