Intradermal medication is neither new nor recent. Tuberculin and vaccines have been so exhibited. Mention is occasionally found of the fact that hay-fever patients have been benefited by intradermal pollen tests. Vaughan1 has advocated the daily subcutaneous injection of small doses of pollen extract in the treatment of hay-fever during the attack. But I cannot find in the literature here available a report of the systematic use of intradermal injections of pollen extract, at one or two day intervals, for the relief of the symptoms of hay-fever.
My purpose here is to report the results in a small series of cases intradermally treated, and the technic employed. These results are so much better than those obtained in previous years on a larger number of patients of the same sort, living in the same community and treated in the usual way with entirely similar pollen extracts, that it seems proper
PHILLIPS EW. RELIEF OF HAY-FEVER BY INTRADERMAL INJECTIONS OF POLLEN EXTRACT. JAMA. 1926;86(3):182–184. doi:10.1001/jama.1926.02670290022008
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