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In doing a biopsy of a new growth, it is our object to remove that portion of the growth in which the cells are young and actively proliferating. This area is at the periphery of the mass. We should accomplish our object with as little discomfort as possible to the patient. If we excise a wedge-shape portion of a growth by means of an ordinary scalpel it is necessary to make three or more separate incisions, and to use thumb forceps, etc. When the lesion is small I have found the use of the ordinary scalpel cumbersome. To obviate some of the difficulties of doing a simple biopsy and to accomplish our object more effectively, I would suggest the use of the knife here described.
This instrument is a scalpel with a blade curved on the flat and with a cutting edge on each side and at its tip. The
Dupin EA. A NEW BIOPSY KNIFE. JAMA. 1926;86(11):749. doi:10.1001/jama.1926.26720370002008c
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