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March 13, 1926


JAMA. 1926;86(11):802. doi:10.1001/jama.1926.02670370072025

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To the Editor:  —In my article on this subject (The Journal, Dec. 12, 1925), the following statement is made: "It is unfortunately rather widely believed without, I think, any proof, that acriflavine injected into the blood stream leaves an impression on the serum which has been rendered, through contact with the dye, highly bactericidal. This belief is based on an experiment made by Browning, whose work is not to be lightly criticized, but the conclusion that he draws was, I am convinced, a curious case of misinterpretation."I have just received from Professor Browning a letter in which he states that he had no intention of implying that the bactericidal properties observed after injection of diaminoacridine sulphate were due to anything else than the presence of acridine compound in the blood and no idea of suggesting that any mysterious bactericidal power was conferred on the serum as a result of

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