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Article
March 20, 1926

EFFECTS OF SUBTOTAL GASTRECTOMY ON GASTRIC SECRETION: EXPERIMENTAL STUDIES BY AID OF A PAWLOW POUCH IN DOGS

JAMA. 1926;86(12):836-839. doi:10.1001/jama.1926.02670380026012
Abstract

The surgical treatment of gastric and duodenal ulcers is still an unsettled question. Those advocating the less radical operations, such as local ulcer resection, gastroenterostomy and pyloroplasty, seem to have permanent results as satisfactory as those which follow more extensive operative procedures, and a decreased mortality to substantiate their claims. The more extensive gastric resections do not appear uniformly to prevent the formation of recurrent ulcers. They may be followed by the reappearance of previous symptom complexes, and they may lead to the establishment of an entirely new clinical picture, due to gastro-intestinal changes. The experimental work reported here was therefore instituted in order to study the changes which occur in the portion of the stomach which remains after subtotal gastrectomy, and to determine the possible mechanism involved. The Pawlow pouch method was considered the most suitable, as the pouch was taken from that part of the stomach which was

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