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March 20, 1926


JAMA. 1926;86(12):887-888. doi:10.1001/jama.1926.02670380077028

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Effect of Sugar in Intensifying the Action of Roentgen Rays on Cancer Cells  In a series of experiments with various substances and roentgen rays, Dr. E. S. Mayer succeeded in intensifying materially the action of roentgen rays by injecting intravenously, in advance, a 10 per cent solution of dextrose. Silberstein had already shown that in cancer tissue a more active metabolism of carbohydrates occurs than in normal tissue. By the administration of insulin he had brought about changes in cancer growth. At the last session of the Gesellschaft der Aerzte, Mayer presented a number of cases of cancer of the larynx in which, by use of the method outlined above, he had effected marked improvement. Not only malignant neoplasms reacted to the treatment but also benign tumors (lymphomas, fibromas) retrogressed more rapidly than otherwise. Injection of the sugar directly into the tumor tissue appears to give better results than the

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