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March 20, 1926


JAMA. 1926;86(12):892. doi:10.1001/jama.1926.02670380082038

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To the Editor:  —It is true that the literature on the pituitary body is a mass of conflicting opinions and theories. The same is true, however, for many of the other ductless glands. Who will set himself up as the authority to decide what clinical symptoms or syndromes are characteristically associated with pathologic changes in the pituitary body, in early as well as the later stages?Cushing has reported cases which clinically simulate the case which I reported as being due to hypersecretion of the suprarenal bodies. Bailey has reported somewhat similar cases as being due to hypersecretion of the pineal body.Barker has described such cases as being due to hypersecretion of the pituitary body.Edward B. Towne, in speaking of ossification changes before the epiphyseal cartilages are ossified, says: "If ossification is incomplete there is excessive skeletal growth resulting in fairly normally proportioned gigantism primarily of pituitary origin."

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