Oil in Capsules.
—Oily or resinous liquids, when given in rather small doses (up to 0.5 cc.), may be conveniently dispensed in hard gelatin capsules. If the dose is only 1 or 2 drops, or if the agent is very irritant, it should be dissolved in a little of some bland oil, such as expressed oil of almond. As examples of medicine best given in this form may be mentioned oleoresin of aspidium, which is used as an anthelmintic against tapeworm in a dosage of from 6 to 8 cc. This dose is best divided into twelve or sixteen capsules, one or two of which are taken every ten minutes, until all are consumed. As another example might be mentioned oil of santal, 0.3 cc., prescribed for subacute urethritis, one or two capsules three times a day after meals.Soft gelatin capsules, generally ovoid, have the advantage over the hard
FANTUS B. THE TECHNIC OF MEDICATION: A SERIES OF ARTICLES ON THE METHODS OF PRESCRIBING AND PREPARING, THE INDICATIONS FOR, AND THE USES OF VARIOUS MEDICAMENTS. JAMA. 1926;86(13):950–951. doi:10.1001/jama.1926.26720390005014a
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