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Article
April 10, 1926

LIVER FUNCTION TESTS: A COMPARATIVE STUDY OF FIVE METHODS IN ONE HUNDRED CLINICAL CASES

JAMA. 1926;86(15):1114-1116. doi:10.1001/jama.1926.02670410010005
Abstract

On our service at Mount Sinai Hospital during the last three years we have performed liver functional tests as a routine. The present report gives the results of 100 cases in which five tests were performed simultaneously, or within an elapsed time of forty-eight hours, which were done in the last year. The tests performed were the van den Bergh test,1 the Widal2 test (hemoclastic crisis), Rosenthal's3 test, examination of the urine for urobilin and urobilinogen, and examination for bile salts in the urine.

THE VAN DEN BERGH TEST  Both the qualitative, which is divided into the immediate direct, biphasic direct, the delayed direct and the indirect, and the quantitative tests were employed. The quantity of bilirubin was expressed in units, the unit being a concentration of 1 in 200,000. We regarded 0.5 unit as the upper limit of normal.

THE WIDAL TEST  We modified the original

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