PERORAL ADMINISTRATION OF LIQUIDS IN GENERAL
Solid dosage forms are, as a general rule, preferable to liquid dosage not only because solids are more easily disguised but also because, in prescribing solutions, we must pay especial attention to the solubility, incompatibility, palatability, and the keeping quality of drugs. Liquid dosage is indispensable: (1) for liquid medicines the dose of which is more than a few drops; (2) for deliquescent and liquefying bodies; (3) for irritant substances, including all highly soluble substances given in fairly large doses, though some of these, especially if the dose is quite large or they are not very soluble, are best prescribed in powder form to be dissolved before taking; (4) for ease of variation in dosage— ascending or descending dosage; (5) when the patient cannot well take solid dosage forms, e. g., for children, or (6) because of somewhat greater rapidity of action.Though all
FANTUS B. THE TECHNIC OF MEDICATION: A SERIES OF ARTICLES ON THE METHODS OF PRESCRIBING AND PREPARING, THE INDICATIONS FOR, AND THE USES OF VARIOUS MEDICAMENTS. JAMA. 1926;86(17):1284–1285. doi:10.1001/jama.1926.26720430004010
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