The universal loss of hair from the body has occasionally been described in medical literature and, although no constant etiologic factor is present in such a condition, various causes have been ascribed, most of them on theoretical grounds. Alopecia areata infrequently produces a universal falling out of the hair. In syphilis loss of hair occurs, but it is seldom complete; Chambers,1 however, in 1901 reported the case of a woman, previously treated for interstitial keratitis, whose hair fell out in patches when she was 5 years old, but it returned in a short time. At the age of 12, her hair began to fall out again, and with the exception of two small, fine ones on the anterior portion of the scalp, she had no hairon the entire body at the age of 20. Arnett2 cited a case which he thought was due to syphilis; the patient was
WILSON G, WINKELMAN NW. GENERALIZED ALOPECIA: REPORT OF THREE CASES, WITH ONE NECROPSY. JAMA. 1926;86(19):1424–1427. doi:10.1001/jama.1926.02670450016006
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