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January 7, 1933

Excitability: A Cardiac Study.

JAMA. 1933;100(1):64. doi:10.1001/jama.1933.02740010064039

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In this volume of the Oxford Medical Publications, the author collects and reviews the papers he has published since 1910 on cardiac excitability. The studies have been based on perfusion of hearts by various modifications of Ringer's solution. From this work he has made some interesting observations on the place of calcium, potassium and phosphorus in the rôle of cardiac excitability and contraction. Based on this, he has set up theories of muscular excitability and contraction, explaining antagonism, inhibition and fatigue. The material is controversial and chiefly of interest to the physiologist and the research student. The manner of presentation is often involved and at times seems flippant. In an attempt to avoid controversy, the bibliography is purposely not complete.

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