In 1901, Dr. J. M. Eager1 of the U. S. Public Health Service, then stationed at Naples, reported a peculiar condition of the enamel of the teeth among Italian emigrants, particularly those coming from Pozzuoli, a community about five miles from Naples. This dental defect was called "denti di Chiaie," after Prof. Stefano Chiaie, who first described the condition. From Eager's description it is recognized as being similar to the enamel defect found in various places in the United States and in other countries and now known as "mottled enamel." The latter designation was first applied by Black2 as a descriptive name for the condition. According to his report, the essential injury is the appearance of the teeth, which are of normal form but not of normal color. When not stained brown or yellow they are a ghastly, opaque white, which comes prominently into notice whenever the lips
MOTTLED ENAMEL. JAMA. 1933;100(3):189–190. doi:10.1001/jama.1933.02740030037014
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