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Before Banting's discovery of insulin, diabetic coma was a serious condition to treat, both in the wards of the hospital and in private practice. Since the advent of insulin, the mortality has diminished to such an extent and with such rapidity that death caused by diabetic coma now appears as unnecessary.
In this article, an attempt is being made to show the difference in mortality before the discovery of insulin and since that time, with especial reference to diabetic coma. For this purpose, all diabetic patients admitted to the wards of St. Luke's Hospital during a period of four years are made subjects of study; they are divided into two groups, group 1 covering the preinsulin and group 2 the postinsulin years.
It will be noted that the first, or preinsulin, group covers the two years just prior to the discovery of insulin, and the second group covers the first
FRISSELL LF, HAJEK J. DIABETIC COMA AND INSULIN. JAMA. 1926;86(25):1903. doi:10.1001/jama.1926.02670510025011
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