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July 3, 1926

Die Malariabehandlung der progressiven Paralyse.

JAMA. 1926;87(1):52-53. doi:10.1001/jama.1926.02680010052032

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This is the most comprehensive work thus far published on the malaria treatment of general paralysis. The book represents an experience of seven years with malaria treatment at the Vienna psychiatric clinic under the directorship of Wagner-Jauregg. While more than a thousand general paralytic patients have been inoculated with malaria, the author deals more particularly with the results in a series of 400 cases treated up to 1922. He thus eliminates from consideration the more recently treated cases, in which the results might be regarded as inconclusive because of the relatively short period that has elapsed since the completion of treatment. The best therapeutic results have been obtained in middle-aged patients in the early stages of general paralysis. As contraindications, the author mentions especially serious heart lesions and obesity. The technic of inoculation is simple. From 2 to 4 cc. of blood is withdrawn from a malaria patient and injected

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