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Suggested by the work of Collip on parathyroidectomized dogs in which the administration of extracts of parathyroid glands raised the calcium content of the blood, this substance was employed in a case of osteitis deformans with a happy result.
Nov. 6, 1923, a retired business man, aged 66, came to seek help for a case of well developed Paget's disease. His mother had died at 72, following a fracture of the hip, and his father at 59, of pneumonia. He had two brothers and one sister, all younger than he and all well. There was no personal history of past illness except scarlet fever at the age of 7 which destroyed the sight of his left eye. About six years previously he noticed a slowly developing stiffness and weakness in his legs between the ankles and knees, which gradually ascended into both thighs. He recorded that the trouble began rather
Bassler A. AN INTERESTING RESULT FROM THE USE OF PARATHYROID EXTRACT IN A CASE OF OSTEITIS DEFORMANS (PAGET'S DISEASE). JAMA. 1926;87(2):96–97. doi:10.1001/jama.1926.92680020001008
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