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February 18, 1933

The Cardiac Output of Man in Health and Disease.

JAMA. 1933;100(7):523. doi:10.1001/jama.1933.02740070061038

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The output of the heart is at present receiving wide attention in clinical and physiologic laboratories interested in the circulatory system. It is highly probable that the determination of the cardiac output will soon take its place with other necessarily available special laboratory tests, such as electrocardiograms, basal metabolic rate determinations and roentgenograms. The author presents this timely subject in a manner at once scholarly and practical. An excellent historical survey accompanied by a comprehensive bibliography introduces the reader to the details of the author's method for determining the output of the heart. This technic is lucidly explained and, for certain purposes, is probably the most satisfactory one now available. It is a "foreign gas," indirect method in which acetylene has been shown to be the gas of choice. The remainder of the book is largely devoted to the presentation of the results of studies made on healthy individuals under

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