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February 25, 1933

THYROTOXICOSIS CONTINUING AFTER EXTREME OPERATIVE, IODINE AND ROENTGEN THERAPY

JAMA. 1933;100(8):568-570. doi:10.1001/jama.1933.27420080001008
Abstract

This case of thyrotoxicosis is reported because of the extreme extent to which the thyroid gland was removed at operation and its remaining portions subsequently destroyed by pole ligations and roentgen treatment. Despite these measures and extensive iodine administration, severe thyrotoxicosis continued, and a complicating infection led to a fatal termination. At autopsy the neck was searched and no thyroid tissue was found.

History.  —A woman, aged 41, seen by Dr. D. P. Abbott, Feb. 27, 1925, because of symptoms of nervousness, weakness, palpitation of the heart, and loss of weight, had been struck, six months previously, in the frontal region by a bolt, producing a depressed fracture of the walls of the frontal sinuses. One month later, an operation was done for the purpose of elevating the depressed bone. Soon after that she began to tire easily and to lose weight, having lost 15 pounds (6.8 Kg.) since the

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