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Article
July 24, 1926

UPPER RESPIRATORY INFECTION AS A CAUSE OF CHOLERA INFANTUM

Author Affiliations

IOWA CITY
From the Department of Pediatrics, State University of Iowa College of Medicine.

JAMA. 1926;87(4):220-223. doi:10.1001/jama.1926.02680040008003
Abstract

A syndrome described under such titles as cholera infantum, alimentary intoxication and anhydremia has long been known. No universal agreement seems to exist as to etiology. In general, parenteral infection has been credited with merely a minor rôle. Some authors mention that the condition may possibly be due to parenteral infection, while others are of the opinion that such infection only ushers in the condition by lowering the patient's resistance. That parenteral infection bears a relationship to gastro-intestinal disturbances is well recognized, but that it may be a direct cause of this most severe type of disturbance has been emphasized only recently.

About a year ago, almost simultaneously, one of us 1 and Marriott2 recorded observations to the effect that a direct relationship may exist between a certain type of acute mastoiditis and "cholera infantum." At the same time the other of us 3 stated that the same clinical

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