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March 4, 1933


JAMA. 1933;100(9):656. doi:10.1001/jama.1933.02740090028010

Obliteration of the larger arterial trunks when due to atheroma, arteriosclerosis or Buerger's disease is a fairly familiar clinical condition. Syphilitic obliteration of the larger vessels, however, would appear from the literature to be a fairly uncommon condition and is not seen often in clinical practice.

The case here reported initiated a search of the literature on the subject and while numerous reports were found of obliteration of the larger vessels as a result of arteriosclerosis and atheroma, the percentage of cases in which the obliteration was due to syphilis would suggest that our case represents a fairly rare condition, or at least one that escapes clinical notice. Encroachment on, and at times complete obliteration of, the orifices of coronaries are frequently seen at postmortem as the result of syphilis of the aorta. However, the larger vessels which leave the aorta are apparently but rarely involved by the syphilitic process

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