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As the basis for this work the authors outline a case in which the earliest and most prominent symptom was agraphia associated later with alexia, left hemianopia, disturbances in showing and naming the fingers of the left hand, left hemiparesis, and disturbances in tactile localization on the left side. The focal diagnosis, confirmed exactly at operation and later at necropsy, placed the lesion at the junction of the angular gyrus with the second occipital convolution. The tumor, though malignant in character, was shelled out without difficulty, and the patient improved greatly for a time. The evolution and disappearance of the symptoms lead to the view that agraphia is an individual disturbance of great localizing value and the relations with apraxia, word-blindness and other forms of aphasic disorder are discussed. The book contains an admirable review of the recorded cases and includes the report of a second case observed by the
Ueber die Agraphie und ihre lokaldiagnostischen Beziehungen. JAMA. 1926;87(6):433. doi:10.1001/jama.1926.02680060057029
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