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Comment & Response
August 11, 2015

Varying Responses to Antithrombotic Treatment by Race/Ethnicity

Author Affiliations
  • 1Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea
  • 2Imperial College, London, England
  • 3Department of Internal Medicine, Pusan National University College of Medicine, Yangsan, Korea
JAMA. 2015;314(6):624-625. doi:10.1001/jama.2015.7381

To the Editor An increasing body of data has shown that East Asian patients have a lower risk of thrombosis and an increased risk of bleeding during antithrombotic treatment for acute coronary syndrome than do white patients.1 The Bivalirudin in Acute Myocardial Infarction vs Heparin and GPI Plus Heparin Trial (BRIGHT) was conducted in China.2 Most of the patients received a loading dose of clopidogrel of 300 mg to 600 mg.

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