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April 22, 1933


JAMA. 1933;100(16):1269-1271. doi:10.1001/jama.1933.02740160053023

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The Susceptibility of Tumors to Radiation  Addressing recently the Medicinisches Doktoren-Kollegium, Dr. Borak discussed "The Susceptibility of Tumors to Radiation." He considered only the behavior of primary tumors, with especial reference to the complete disappearance of the neoplasm. Probably all tissues may be influenced by roentgen or radium irradiation, but most of them are damaged only in a qualitative sense (degeneration) or quantitative sense (atrophy), and in only a few is a complete anatomic destruction brought about. A malignant tumor has always the same or a greater susceptibility to radiation than its mother-tissue. If a given tumor is derived from a tissue in which a complete destruction is possible, then a complete destruction of the tumor itself can be effected. Such tumors may be termed "susceptible to irradiation by nature." To this class belong tumors of the testis, tumors of the ovary, derived from the ovarian follicles; the lymphosarcomas; the

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