Fetal syphilis, fetal anomalies, toxemias of pregnancy and maternal acute infections have long been recognized as causes of intra-uterine fetal death at any time during pregnancy. When no cause could be demonstrated for the death of the fetus, cases were classified as idiopathic. In the last decade certain observers, namely, De Lee1 and Curtis,2 have assumed and have more or less completely verified infectious organisms as the cause for intra-uterine fetal death. Of necessity, the verification beyond a reasonable doubt of such organisms being the cause of the death of the fetus in utero presents numerous obstacles, and in many instances only probable or presumable data can be obtained in support of such a view. It would seem important, in view of the limited number of cases on record, to study as completely as possible cases that give indication of falling into this class, and to place them
BROWNE WH, KINCAID HL. ETIOLOGY AND DIAGNOSIS OF INTRA-UTERINE FETAL DEATH: REPORT OF CASE, WITH EXPERIMENTAL STUDY. JAMA. 1926;87(11):847–848. doi:10.1001/jama.1926.02680110047014
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