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To the Editor:
—In the editorial comment on serum amylase (The Journal, March 11) appears the following: "Chemical examination of the blood... has displaced the older chemical examination of the urine in several directions, such as for the study of the diabetic state." Such a statement is not in accord with the facts. When studying the diabetic state the physician is primarily concerned with the metabolism of carbohydrate and the ability of the patient to utilize the carbohydrate ingested. Blood sugar estimations are of occasional importance in determining the existence of the diabetic state; i. e., in differentiating true diabetes from nondiabetic glycosuria. Occasionally the renal threshold for dextrose is so high that glycosuria does not occur in the diabetic state, so that blood sugar determinations afford the best means of ascertaining the individual's carbohydrate metabolism. But after the diagnosis of diabetes has been established and the renal threshold value
Boyer EH. LABORATORY EXAMINATIONS IN DIABETES AND IN GASTRIC DISORDERS. JAMA. 1933;100(17):1358–1359. doi:10.1001/jama.1933.02740170056027
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