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Comment & Response
August 18, 2015

Common Cold Treatment Using Zinc—Reply

Author Affiliations
  • 1Department of Pediatrics, All India Institute of Medical Sciences, Bhubaneswar, India
  • 2Department of Pediatrics, Post-Graduate Institute of Medical Education and Research, Chandigarh, India
JAMA. 2015;314(7):730. doi:10.1001/jama.2015.8177

In Reply The findings reported in the JAMA Clinical Evidence Synopsis were based on randomized clinical trials, as was our Cochrane review.1 The comparison of the 2 doses (≥75 mg/d vs <75 mg/d) of zinc was performed as a part of a network meta-analysis, which is a valid technique to assess the comparative effectiveness of interventions among similar study populations that have not been compared directly in randomized clinical trials.2